KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFAS
All Species:
22.73
Human Site:
S128
Identified Species:
41.67
UniProt:
O15067
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15067
NP_036525
1338
144724
S128
T
T
R
R
Y
R
L
S
F
A
H
P
P
S
A
Chimpanzee
Pan troglodytes
XP_511854
1397
150781
S187
T
T
R
R
Y
R
L
S
F
A
H
P
P
S
A
Rhesus Macaque
Macaca mulatta
XP_001112405
1335
144369
S128
T
T
R
R
Y
R
L
S
F
A
H
P
P
S
A
Dog
Lupus familis
XP_850167
1368
147436
S128
T
T
R
R
Y
L
L
S
F
A
H
P
P
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUR0
1337
144611
S128
T
T
R
R
Y
R
L
S
F
T
D
H
P
T
A
Rat
Rattus norvegicus
NP_001099261
1271
136879
L129
L
A
L
D
S
W
D
L
D
F
Y
T
K
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038667
1314
142462
G125
H
L
I
K
P
Q
E
G
C
K
V
G
M
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35421
1354
148067
T128
T
S
T
R
Y
L
V
T
F
G
E
G
S
K
A
Honey Bee
Apis mellifera
XP_625036
1243
138433
I125
E
Y
K
Y
M
K
P
I
K
T
F
D
H
G
F
Nematode Worm
Caenorhab. elegans
Q19311
1343
148611
E125
R
G
I
R
Y
L
V
E
D
D
V
D
V
N
E
Sea Urchin
Strong. purpuratus
XP_781955
1205
129101
T128
R
S
R
R
F
L
I
T
A
T
K
P
S
V
L
Poplar Tree
Populus trichocarpa
XP_002315209
1377
150616
Y182
R
S
R
R
Y
L
L
Y
S
K
G
V
L
P
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8D3
1387
151761
F193
R
S
R
R
Y
L
L
F
S
K
E
P
L
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
97.1
87.5
N.A.
88.5
84
N.A.
N.A.
N.A.
N.A.
63.2
N.A.
50.5
50.1
47.5
52.4
Protein Similarity:
100
95.2
98
91.6
N.A.
92.8
88.6
N.A.
N.A.
N.A.
N.A.
75.1
N.A.
66
66.2
64.1
65.4
P-Site Identity:
100
100
100
86.6
N.A.
73.3
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
33.3
0
13.3
20
P-Site Similarity:
100
100
100
86.6
N.A.
80
6.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
53.3
13.3
26.6
46.6
Percent
Protein Identity:
50.3
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
65.2
N.A.
N.A.
65.3
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
8
31
0
0
0
0
39
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
16
8
8
16
0
0
16
% D
% Glu:
8
0
0
0
0
0
8
8
0
0
16
0
0
0
16
% E
% Phe:
0
0
0
0
8
0
0
8
47
8
8
0
0
0
16
% F
% Gly:
0
8
0
0
0
0
0
8
0
8
8
16
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
31
8
8
0
0
% H
% Ile:
0
0
16
0
0
0
8
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
8
0
0
8
24
8
0
8
16
0
% K
% Leu:
8
8
8
0
0
47
54
8
0
0
0
0
16
8
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
8
0
8
0
0
0
0
47
39
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
31
0
62
77
0
31
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
31
0
0
8
0
0
39
16
0
0
0
16
31
0
% S
% Thr:
47
39
8
0
0
0
0
16
0
24
0
8
0
8
8
% T
% Val:
0
0
0
0
0
0
16
0
0
0
16
8
8
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
70
0
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _